Answers to common questions about bromoaniline

Basic Information:

Alias: 4-Bromoaniline, p-Bromoaniline

CAS No: 106-40-1

Molecular Formula: C6H6BrN

Molecular Weight: 172.02

Physical State:White to light yellow to light orange solid

Melting Point:56-62°C (lit.)

Boiling Point:230-250°C

Uses:Used in the manufacturing of azo dyes and organic synthesis

Employed in the preparation of dihydroquinazoline

Q: What is4-Bromoaniline?

A: 4-Bromoaniline is an organic compound with the molecular formula C6H6BrN. It is a brominated derivative of aniline, where the molecular structure consists of a benzene ring, with one hydrogen atom replaced by an amino group (-NH2) and another hydrogen atom replaced by a bromine atom (Br) at the para position. p-Bromoaniline typically appears as a white or pale yellow solid, possessing distinct chemical and physical properties.

Q: What are the main uses of 4-Bromoaniline?

A: 4-Bromoaniline is primarily used in organic synthesis and chemical research. Industrially, it serves as an important intermediate for the synthesis of dyes, pesticides, pharmaceuticals, and other organic compounds. Due to the reactivity of its amino and bromine groups, 4-Bromoaniline can participate in various chemical reactions, producing different organic products.

Q: What are the chemical properties of 4-Bromoaniline?

A: 4-Bromoaniline has several key chemical properties:

Basicity: 4-Bromoaniline is basic and can react with acids to form salts.

Reactivity of the bromine atom: The bromine atom can undergo nucleophilic substitution reactions, making 4-Bromoaniline a valuable intermediate in organic synthesis.

Reactivity of the amino group: The amino group can undergo various reactions, such as acylation, nitration, and diazotization.

Q: What are the physical properties of 4-Bromoaniline?

A: 4-Bromoaniline is a white to pale yellow crystalline substance with a specific melting and boiling point. Its melting point ranges from approximately 66°C to 70°C, and its boiling point is around 240°C. p-Bromoaniline has some volatility at room temperature and is soluble in organic solvents such as ethanol and ether, but has low solubility in water.

Q: How safe is 4-Bromoaniline?

A: 4-Bromoaniline is moderately toxic and should be handled with care. Exposure to 4-Bromoaniline may cause skin and eye irritation, while inhalation of its vapors or dust can have harmful effects on the respiratory system. When handling p-Bromoaniline, proper protective equipment, such as gloves and goggles, should be worn, and it should be used in a well-ventilated area. Waste disposal should follow local environmental regulations.

Q: How should 4-Bromoaniline be stored?

A: 4-Bromoaniline should be stored in a tightly sealed container in a cool, dry, well-ventilated area, away from sources of heat or ignition. The storage environment should avoid direct sunlight and high temperatures to prevent decomposition or volatilization. Additionally, p-Bromoaniline should be kept away from oxidizing agents and acidic substances to avoid chemical reactions.

Q: What are the production methods for 4-Bromoaniline?

A: The production of 4-Bromoaniline mainly involves two methods:

Direct bromination: 4-Bromoaniline can be produced by direct bromination of aniline, yielding both 4-Bromoaniline and o-Bromoaniline. The 4-Bromoaniline is then separated and purified.

Diazotization-bromination: Aniline is first diazotized to form a diazonium salt, followed by bromination in the presence of copper salts, yielding 4-Bromoaniline.

As an important organic compound, 4-Bromoaniline finds wide applications in chemical industries and research. Understanding its chemical properties, uses, safety, and storage methods is crucial for scientific research and industrial production. When handling 4-Bromoaniline, strict safety regulations must be followed to ensure the safety of personnel and the environment.

4-Bromoaniline is a versatile and widely used chemical. It plays an important role in various fields, such as pesticides, dyes, pharmaceuticals, organic synthesis, and electronic materials. With advances in technology and the expansion of application areas, the demand and prospects for 4-Bromoaniline are expected to grow.