Chemical Properties and Industrial Applications of 3-Methyl-6-nitro-1H-indazole

Alias: 3-Methyl-6-nitro-1H-indazole

CAS No: 6494-19-5

Molecular Formula: C8H7N3O2

Molecular Weight: 177.16

Physical State: Solid powder

Melting Point: 187-188°C

Boiling Point: 384.9±22.0 °C (Predicted)

Density: 1.437

Applications: Used as an organic intermediate and pharmaceutical intermediate.

3-methyl-6-nitro-1H-indazole (CAS No.: 6494-19-5): Chemical Properties and Industrial Applications

3-Methyl-6-nitro-1H-indazole is an important organic chemical compound with broad applications, especially in organic synthesis and the pharmaceutical industry. Its chemical properties and applications are of significant importance for scientific research and industrial production. This article will provide a detailed introduction to its basic chemical properties, physical characteristics, and main application areas.

1. Basic Chemical Properties

3-Methyl-6-nitro-1H-indazole has the molecular formula C8H7N3O2 and a molecular weight of 177.16. This compound consists of an indazole ring structure with methyl and nitro substituents. The introduction of the nitro and methyl groups imparts special chemical reactivity, making it an important component in organic synthesis.

The melting point of this compound is 187-188°C, and the boiling point is 384.9±22.0°C (predicted value). Its density is 1.437 g/cm³. It exists in the form of solid powder and has good stability, making it suitable for use in various chemical reactions.

2. Physical Properties

The physical properties of 3-methyl-6-nitro-1H-indazole enable it to exhibit high adaptability in many industrial processes. It has a high melting point and boiling point, indicating that the compound remains stable even under high-temperature conditions. In industrial production, this property makes it more widely applicable in reactions conducted in high-temperature environments.

Moreover, its density suggests that the substance is a compact solid, which makes it easy to handle during storage and transportation.

3. Industrial Applications

3-Methyl-6-nitro-1H-indazole is widely used in the synthesis of organic intermediates and pharmaceutical intermediates. Due to the presence of reactive nitro and methyl substituents in its structure, it plays a significant role in various organic synthesis reactions, especially in the pharmaceutical industry, where it serves as an active intermediate in drug synthesis.

Organic Intermediates

As an important intermediate in organic synthesis, 3-methyl-6-nitro-1H-indazole  can be used to synthesize various chemicals and pharmaceutical intermediates. Its unique structure gives it high reactivity, especially in the construction of cyclic structures.

Pharmaceutical Intermediates

In the pharmaceutical industry, 3-methyl-6-nitro-1H-indazole acts as a pharmaceutical intermediate, participating in the synthesis of various drugs. As an effective starting material, it plays a key role in the production of drugs such as those used for antibacterial and antiviral purposes.

Conclusion

3-methyl-6-nitro-1H-indazole (CAS No.: 6494-19-5) is an essential raw material in organic chemistry and the pharmaceutical industry due to its excellent chemical properties and broad application prospects. Whether in organic synthesis or pharmaceutical intermediate production, it plays a critical role. As technology advances and demand increases, this compound is expected to find further applications in more industrial fields.