Frequently Asked Questions (FAQ) about 3-Methyl-6-Nitro-1H-Indazole

Alias: 3-Methyl-6-nitro-1H-indazole

CAS No: 6494-19-5

Molecular Formula: C8H7N3O2

Molecular Weight: 177.16

Physical State: Solid powder

Melting Point: 187-188°C

Boiling Point: 384.9±22.0 °C (Predicted)

Density: 1.437

Applications: Used as an organic intermediate and pharmaceutical intermediate.

3-Methyl-6-nitro-1H-indazole (CAS No. 6494-19-5) is an important organic compound with a wide range of industrial applications, particularly in the pharmaceutical and organic synthesis fields. This article will answer some common questions about 3-methyl-6-nitro-1H-indazole  to help you better understand its properties, uses, and related information.

1. What is 3-Methyl-6-Nitro-1H-Indazole?

3-Methyl-6-nitro-1H-indazole is an organic compound containing an indazole ring structure, with the molecular formula C8H7N3O2 and a molecular weight of 177.16. Its structure includes two substituents: a methyl group (-CH3) and a nitro group (-NO2), which make it highly reactive in chemical reactions. It is widely used in organic synthesis and as a pharmaceutical intermediate.

2. What are the main applications of 3-Methyl-6-Nitro-1H-Indazole?

3-Methyl-6-nitro-1H-indazole is primarily used in the following fields:

Pharmaceutical Industry: As a drug intermediate, it is involved in the synthesis of antibacterial, antiviral, and other therapeutic drugs.

Organic Synthesis: It is used as an intermediate in the synthesis of various organic compounds, such as pesticides, dyes, and polymers.

Catalyst Applications: In some organic reactions, 3-methyl-6-nitro-1H-indazole  can serve as a catalyst or reaction medium.

Dyes and Pigments: As a raw material for the synthesis of dyes and pigments, it finds applications in industries such as textiles, plastics, and leather.

3. What are the physical properties of 3-Methyl-6-Nitro-1H-Indazole?

The physical properties of 3-methyl-6-nitro-1H-indazole include:

Melting Point: 187-188°C

Boiling Point: 384.9±22.0°C (estimated)

Density: 1.437 g/cm³

Physical State: Solid powder These properties make it stable under high temperatures, suitable for various industrial applications.

4. How is 3-methyl-6-nitro-1H-indazole synthesized?

The synthesis of 3-methyl-6-nitro-1H-indazole typically involves modifications to the indazole ring structure. Common methods include methylation and nitration reactions. Methylation is often carried out using methylating agents, while nitration is performed using a mixture of nitric acid and sulfuric acid. These steps, under suitable reaction conditions, yield 3-methyl-6-nitro-1H-indazole.

5. Does 3-Methyl-6-Nitro-1H-Indazole have toxicity?

3-Methyl-6-nitro-1H-indazole does not exhibit significant toxicity under normal usage conditions. However, like many organic chemicals, it can be harmful to humans if used improperly or in excessive amounts. It is recommended to wear appropriate protective equipment, such as gloves, masks, and safety goggles, and to follow proper safety procedures during handling.

6. What is the environmental impact of 3-methyl-6-nitro-1H-indazole ?

3-Methyl-6-nitro-1H-indazole may cause pollution to water bodies and soil if not properly handled. Therefore, it is important to follow environmental regulations during its use and disposal. Large-scale release into the environment should be avoided to reduce its impact on ecosystems. Specific environmental impact studies need to be conducted based on the application scenario.

7. What are the detection methods for 3-Methyl-6-Nitro-1H-Indazole?

Common detection methods for 3-methyl-6-nitro-1H-indazole include

High-Performance Liquid Chromatography (HPLC): Suitable for accurately determining its purity and concentration.

Gas Chromatography (GC): Suitable for analyzing volatile components, especially in complex samples for qualitative and quantitative analysis.

Ultraviolet-Visible Spectroscopy (UV-Vis): Used to analyze its optical properties and purity, especially for quick determination. These methods can effectively help monitor product quality and ensure it meets industrial application standards.

8. How should 3-methyl-6-nitro-1H-indazole  be stored?

3-Methyl-6-nitro-1H-indazole should be stored in a dry, cool place, away from high temperatures and humidity. It should be kept sealed to avoid contact with oxidizing agents or strong acids and bases, which could lead to chemical reactions. During storage and transportation, it is important to adhere to chemical safety management regulations.

9. How can I purchase 3-methyl-6-nitro-1H-indazole ?

3-Methyl-6-nitro-1H-indazole can be purchased from chemical suppliers or pharmaceutical intermediate suppliers. When purchasing, ensure that the supplier is qualified and that the product quality meets your needs. If you have any questions about the product or require technical support, you can contact us directly.

Conclusion

3-methyl-6-nitro-1H-indazole , as an important organic chemical intermediate, has a broad range of applications. From pharmaceuticals and pesticides to organic synthesis, dyes, and catalysts, it holds significant value. Understanding its common issues can help us better grasp its properties and uses, ensuring safe and efficient utilization in industrial production. For further inquiries or requirements, feel free to contact us!