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Name | Tetrahydro-4H-pyran-4-one |
Basic Information | |
Synonyms | Tetrahydro-4-pyrone; TETRAHYDRO-GAMMA-PYRONE; TETRAHYDROPYRAN-4-ONE; TETRAHYDRO-4H-PYRAN-4-ONE; |
CAS number | 29943-42-8 |
EINECS | 249-967-2 |
Formula | C5H8O2 |
Molecular Weight | 100.12 |
Flashing Point | 134 °F |
Water Solubility | MISCIBLE |
Boiling Point | 166-166.5 °C(lit.) |
Density | 1.084 g/mL at 25 °C(lit.) |
Storage temp | Keep Cold |
Refractive index | n20/D 1.452(lit.) |
Safety Information | |
Hazard Codes | Xi,F |
Risk Statements | 10-36/37/38 |
Safety Statements | 24/25-36-26 |
RIDADR | UN 1224 3/PG 3 |
HazardClass | 3.2 |
PackingGroup | III |
HS Code | 29329995 |
Description | |
Tetrahydro-4H-pyran-4-one is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes. The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. Tetrahydro-4H-pyran-4-one is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3. |
Name | Tetrahydro-4H-pyran-4-one |
Basic Information | |
Synonyms | Tetrahydro-4-pyrone; TETRAHYDRO-GAMMA-PYRONE; TETRAHYDROPYRAN-4-ONE; TETRAHYDRO-4H-PYRAN-4-ONE; |
CAS number | 29943-42-8 |
EINECS | 249-967-2 |
Formula | C5H8O2 |
Molecular Weight | 100.12 |
Flashing Point | 134 °F |
Water Solubility | MISCIBLE |
Boiling Point | 166-166.5 °C(lit.) |
Density | 1.084 g/mL at 25 °C(lit.) |
Storage temp | Keep Cold |
Refractive index | n20/D 1.452(lit.) |
Safety Information | |
Hazard Codes | Xi,F |
Risk Statements | 10-36/37/38 |
Safety Statements | 24/25-36-26 |
RIDADR | UN 1224 3/PG 3 |
HazardClass | 3.2 |
PackingGroup | III |
HS Code | 29329995 |
Description | |
Tetrahydro-4H-pyran-4-one is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes. The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. Tetrahydro-4H-pyran-4-one is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3. |
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