Frequently Asked Questions about 3-Methyl-6-nitro-1H-Indazole

Alias: 3-Methyl-6-nitro-1H-indazole

CAS No: 6494-19-5

Molecular Formula: C8H7N3O2

Molecular Weight: 177.16

Physical State: Solid powder

Melting Point: 187-188°C

Boiling Point: 384.9±22.0 °C (Predicted)

Density: 1.437

Applications: Used as an organic intermediate and pharmaceutical intermediate.

3-Methyl-6-nitro-1H-Indazole (CAS Number: 6494-19-5) is an important organic chemical compound with a wide range of industrial applications, especially in the pharmaceutical and organic synthesis fields. This article will address some common questions about 3-methyl-6-nitro-1H-indazole to help you better understand its properties, uses, and relevant information.

1. What is 3-Methyl-6-nitro-1H-Indazole?

   3-Methyl-6-nitro-1H-Indazole is an organic compound containing an indazole ring structure with the molecular formula C8H7N3O2 and a molecular weight of 177.16. Its structure includes two substituents, a methyl group (-CH3) and a nitro group (-NO2), which make it highly reactive in chemical reactions. It is widely used in organic synthesis and the production of pharmaceutical intermediates.

2. What are the main applications of 3-Methyl-6-nitro-1H-Indazole?

   3-Methyl-6-nitro-1H-Indazole is primarily used in the following fields:

•    Pharmaceutical Industry: It serves as an intermediate for the synthesis of antibacterial, antiviral, and other therapeutic drugs.

•    Organic Synthesis: As an intermediate in chemical reactions, it is widely used in the synthesis of various organic compounds, such as pesticides, dyes, and polymers.

•    Catalyst Applications: In certain organic reactions, 3-Methyl-6-nitro-1H-Indazole can act as a catalyst or reaction medium.

•    Dyes and Pigments: It is used as a raw material for the synthesis of dyes and pigments in industries such as textiles, plastics, and leather.

3. What are the physical properties of 3-Methyl-6-nitro-1H-Indazole?

   The physical properties of 3-methyl-6-nitro-1H-indazole  are:

•    Melting Point: 187-188°C

•    Boiling Point: 384.9±22.0°C (predicted value)

•    Density: 1.437 g/cm³

•    Physical State: Solid powder

   These properties make it stable even under high temperature conditions, suitable for various industrial applications.

4. How is 3-Methyl-6-nitro-1H-Indazole synthesized?

   The synthesis of 3-Methyl-6-nitro-1H-Indazole typically involves modifications to the indazole ring structure, with methylation and nitration reactions being common synthesis methods. Methylation usually uses methylating agents, while nitration is performed with a mixture of nitric acid and sulfuric acid. These steps yield 3-methyl-6-nitro-1H-indazole under suitable reaction conditions.

5. Does 3-Methyl-6-nitro-1H-Indazole have toxicity?

   3-Methyl-6-nitro-1H-Indazole does not exhibit significant toxicity under normal usage conditions. However, like many organic chemicals, it can pose health risks if handled improperly or in excessive amounts. It is recommended to wear appropriate personal protective equipment (PPE) such as gloves, masks, and safety goggles, and to follow relevant safety protocols during handling.

6. What is the environmental impact of 3-methyl-6-nitro-1H-indazole ?

   3-Methyl-6-nitro-1H-Indazole may cause pollution to water bodies and soil if not properly managed. Therefore, it is essential to follow environmental regulations during use and disposal. Large-scale discharge into the environment should be avoided to minimize its impact on ecosystems. Specific environmental impact studies should be conducted based on different application scenarios.

7. What are the detection methods for 3-Methyl-6-nitro-1H-Indazole?

•    Common detection methods for 3-Methyl-6-nitro-1H-Indazole include:

•    High-Performance Liquid Chromatography (HPLC): Suitable for accurately determining its purity and concentration.

•    Gas Chromatography (GC): Used for analyzing its volatile components, especially in complex samples for qualitative and quantitative analysis.

•    Ultraviolet-Visible Spectroscopy (UV-Vis): Used for analyzing its optical properties and purity, particularly for rapid determination.

•    These methods effectively help monitor product quality and ensure compliance with industrial application standards.

8. How should 3-Methyl-6-nitro-1H-Indazole be stored?

   3-Methyl-6-nitro-1H-Indazole should be stored in a dry, cool place, avoiding high temperatures and humid environments. It should be sealed in airtight containers and kept away from oxidizing agents or strong acids and bases to prevent chemical reactions. During storage and transportation, ensure compliance with chemical safety management regulations.

9. How can 3-Methyl-6-nitro-1H-Indazole be purchased?

 3-methyl-6-nitro-1H-indazole  can be purchased from chemical suppliers or pharmaceutical intermediate suppliers. When purchasing, confirm the supplier’s credentials and product quality to ensure the product meets your requirements. If you have any questions or need technical support, feel free to contact us directly.

3-Methyl-6-nitro-1H-Indazole, as an important organic chemical intermediate, has a broad range of application prospects. From pharmaceuticals, pesticides, and organic synthesis to dyes and catalysts, it demonstrates significant value. Understanding its frequently asked questions can help us better grasp its properties and applications, ensuring safe and efficient use in industrial production. If you have any further needs or questions, feel free to contact us at any time!